Scientific references
 

Scientific articles
 
   List of scientific references describing applications of GENOVAC antibodies (49 KB)
 
12/07Zeisel M et al. (2007): Scavenger receptor class B type I is a key host factor for hepatitis C virus infection required for an entry step closely linked to CD81. Hepatology, 46/6:1722-31
  
05/07Catanese MT et al. (2007): High avidity monoclonal antibodies against human scavenger receptor class B type I efficiently block hepatitis C virus infection in the presence of HDL. J Virol, 2007 0: JVI.00193-07
  
04/07Schreiner A et al. (2007): Junction protein Shrew-1 influences cell invasion and interacts with invasion-promoting protein CD147. Mol Biol Cell, 18/4:1272-81
  
02/07Chan CHF et al. (2007): Colorectal Hyperplasia and Dysplasia Due to Human Carcinoembryonic Antigen (CEA) Family Member Expression in Transgenic Mice. PLoS ONE, 2/12: e1353
  
01/07Viswanathan A et al. (2007): Functional expression of N-formyl peptide receptors in human bone marrow-derived mesenchymal stem cells. Stem Cells, 25/5:1263-9
  
12/06Weinberg AD et al. (2006): Anti-OX40 (CD134) Administration to nonhuman primates: immunostimulatory effects and toxicokinetic study. J Immunother, 29/6: 575-585
  
11/06Ellies D et al. (2006): Bone density ligand, sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity. J Bone Miner Res, 21/11:1738-49
  
10/06D'Amour K et al (2006): Production of pancreatic hormone–expressing endocrine cells from human embryonic stem cells. Nat Biotechnol, 24/1: 1392-1401
  
09/06Technology Feature: 'Chain gang' delivers for hard labor. Nature Methods, 3/9: 753-762
  
04/06Krause S et al. (2006): Blockade of interleukin-13-mediated cell activation by a novel inhibitory antibody to human IL-13 receptor α1. Mol Immunol, 33/11: 1799-1807
  
04/06Avadhanula V et al. (2006): Respiratory viruses augment the adhesion of bacterial pathogens to respiratory epithelium in a viral species- and cell type-dependent manner. J Virol, 80/4: 1629–1636
  
03/06Nöckel J et al (2006): Characterization of gastric adenocarcinoma cell lines established from CEA424/SV40 T antigen-transgenic mice with or without a human CEA transgene. BMC Cancer, 6: 57
  
02/06Pavoni E et al. (2006): Selection, affinity maturation, and characterization of a human scFv antibody against CEA protein. BMC Cancer, 6: 41
  
11/05Klaile E et al (2005): CEACAM1 functionally interacts with filamin A and exerts a dual role in the regulation of cell migration. JCS, 118: 5513-5524
  
11/05Bade B et al (2005): Differential expression of the granzymes A, B, K, M and perforin in human peripheral blood lymphocytes. Int. Immunol, 17: 1419-1428
  
10/05D’Amour K et al. (2005): Efficient differentiation of human embryonic stem cells to definitive endoderm. Nat Biotechnol, 23: 1534-1541
  
10/05Bade B et al (2005): Detection of soluble human granzyme K in vitro and in vivo. Eur J Immunol, 35/10:2940-2948
  
10/05Bratke K et al (2005): Differential expression of human granzymes A, B, and K in natural killer cells and during CD8+ T cell differentiation in peripheral blood. Eur J Immunol, 35/9: 2608-2616
  
10/05Bade B et al. (2005): Detection of soluble human granzyme K in vitro and in vivo. Eur J Immunol, 35/10:2940-2948
  
09/05Roessler et al (2005): Identification of Nicotinamide N-Methyltransferase as a Novel Serum Tumor Marker for Colorectal Cancer. Clin Cancer Res, 11/18: 6550-6558
  
08/05Muenzner P et al (2005): CEACAM engagement by human pathogens enhances cell adhesion and counteracts bacteria-induced detachment of epithelial cells. JBC, 170/5: 825-836
  
04/05Kalina T et al (2005): Myeloid antigens in childhood lymphoblastic leukemia: clinical data point to regulation of CD66c distinct from other myeloid antigens. BMC Cancer 5: 38
  
04/05Kunii R et al. (2005): Expression of CD13/aminopeptidase N on human gingival fibroblasts and up-regulation upon stimulation with interleukin-4 and interleukin-13. J Periodontal Res, 40/2:138-46
  
12/04Nanda A et al. (2004): Identification of a binding partner for the endothelial cell surface proteins TEM7 and TEM7R. Cancer Res, 64: 8507–8511.
  
10/04Kammerer R et al. (2004): The tumour suppressor gene CEACAM1 is completely but reversibly downregulated in renal cell carcinoma. J Pathol, 204/3: 258-267.
  
09/04Haynes C and BS Schnierle (2004): Retroviral vector targeting through insertion of epidermal growth factor into receptor binding deficient influenza A hemagglutinin results in fusion defective particles. J Virol Methods, 120/2: 189-199
  
09/04Kiessling J et al. (2004): Dual targeting of plastid division protein FtsZ to chloroplasts and the cytoplasm. EMBO reports 5 /9: 889-894.
  
08/04Myrtek D et al. (2004): Expression of interleukin-13 receptor a 1-subunit on peripheral blood eosinophils is regulated by cytokines. Immunology, 112: 597–604.
  
05/04McCaw S et al. (2004): Engulfment of Neisseria gonorrhoeae: Revealing distinct processes of bacterial entry by individual carcinoembryonic antigen-related cellular adhesion molecule family receptors. Infect Immun, 72/5: 2742–2752.
  
01/04Schmitter T et al. (2004): Granulocyte CEACAM3 is a phagocytic receptor of the innate immune system that mediates recognition and elimination of human-specific pathogens. J Exp Med, 199/1: 35–46.
  
01/04Elagoz A et al. (2004): A truncated form of CKb8-1 is a potent agonist for human formyl peptide-receptor-like 1 receptor. Br J Pharmacol, 141/1: 37-46.
  
01/04Bharti S (2004): Novel membrane protein shrew-1 targets to Cadherin-mediated junctions in polarized epithelial cells. Mol Biol Cell, 15: 397–406.
  
12/03Fahlgren A et al. (2003): Interferon-gamma tempers the expression of carcinoembryonic antigen family molecules in human colon cells: a possible role in innate mucosal defence. Scand J Immunol, 58/6:628-641.
  
11/03de Jonge MI et al. (2003): Mapping the binding domains on meningococcal Opa proteins for CEACAM1 and CEA receptors. Mol Microbiol, 50/3: 1005
  
10/03A shortcut from genomics to drug development. By Jens Lohrmann, Stefan Lang and John Thompson, published in Current Drug Discovery, October 2003. (For reprints please contact Dr. Stefan Lang or download article as a PDF document.)
  
05/03de Jonge MI et al. (2003): Functional activity of antibodies against the recombinant OpaJ protein from Neisseria meningitides. Infection and Immunity, 71/5:2331-2340.
  
02/03Custom-made Antibodies Produced by Genetic Immunisation: Applications in Drug Development, Therapy and Diagnosis. By Stefan Lang and John Thompson, published in Global Outsourcing Review, Vol. 5, No. 1, Spring 2003. (For reprints please contact Dr. Stefan Lang or download article as a PDF document.)
  
12/02Genetische Immunisierung zur Antikörperproduktion. Von Stefan Lang und John Thompson, veröffentlicht in transkript, 12/02, 8.Jahrgang. (Text only in German. For reprints please contact Dr. Stefan Lang or download article as a PDF document.)
  
10/02Bioprocessing - Genetic Immunization for Antibody Production. Tutorial: Genovac's Technological Shortcut From Gene to Antibody. By John Thompson, Ph.D., and Stefan Lang, Ph.D., published in Genetic Engineering News, Vol. 22, No. 17, October 1, 2002 (For reprints please contact Dr. Stefan Lang.)
  
10/02Klippel S et al. (2002): Biochemical characterisation of PRV-1, a novel hematopoietic cell surface receptor, which is overexpressed in polycythemia rubra vera. Blood, 100/7: 2441-2448.
  
09/02Genetische Immunisierung – ein hocheffizientes Verfahren zur Antikörper-Herstellung für die medizinische Diagnostik und Therapie. Von Stefan Lang und John Thompson, veröffentlicht in BIOspektrum, Sonderausgabe Proteomics & Drug Development, 8.Jahrgang. (Text only in German. For reprints please contact Dr. Stefan Lang or download article as a PDF document.)
  
08/02Bioprocessing - Capacity Mismatch for Production of Monoclonals: Development-Stage Enhancements Alleviate Bottleneck. By Angelo DePalma, Ph.D., published in Genetic Engineering News, Vol. 22, No. 14, August 2002 (For reprints please contact Dr. Stefan Lang.)
  
04/02Billker O et al. (2002): Distinct mechanisms of internalisation of Neisseria gonorrhoeae by members of the CEACAM receptor family involving Pac1- and Cdc42-dependent and –independent pathways. EMBO J, 21/4: 560-571.
  
03/02Boulton IC and SD Gray-Owen (2002): Neisserial binding to CEACAM1 arrests the activation and proliferation of CD4+ T lymphocytes. Nat Immunol, 3/3:229-236
  
09/01Watt SM et al. (2001): Homophilic adhesion of human CEACAM1 involves N-terminal domain interactions: structural analysis of the binding site. Blood, 98/5: 1469-1479
  
09/01Richter G. et al. (2001): Tumor necrosis factor -alpha regulates the expression of ICOS ligand on CD34+ progenitor cells during differentiation into antigen presenting cells. J Biol Chem, 276/49: 45686-93.
  
04/00Temerinac S et al. (2000): Cloning of PRV-1, a novel member of the uPAR receptor superfamily, which is overexpressed in polycythemia rubra vera. Blood, 95/8: 2569-2576.
  
02/00Schoelzel S et al. (2000): Carcinoembryonic antigen family members CEACAM6 and CEACAM7 are differentially expressed in normal tissues and oppositely deregulated in hyperplastic colorectal polyps and early adenomas. Am J Pathol, 156/2: 595-605
  
 
   
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